Enclomiphene Guide (2026)
Blocks estrogen receptors in the hypothalamus and pituitary gland, increasing GnRH, LH, and FSH secretion to stimulate natural testosterone production while preserving fertility.
$40-90/mo
Compounded Price
Daily
Frequency
3
Dose Options
Not yet FDA-approved (available compounded)
FDA Approved
What Is Enclomiphene?
Enclomiphene is a Selective estrogen receptor modulator (SERM) that works by blocks estrogen receptors in the hypothalamus and pituitary gland, increasing gnrh, lh, and fsh secretion to stimulate natural testosterone production while preserving fertility. It was approved by the FDA in Not yet FDA-approved (available compounded) and is manufactured by Various compounding pharmacies.
Brand names include Androxal (not yet FDA-approved). Enclomiphene is administered as a daily oral pill.
How Enclomiphene Works
Blocks estrogen receptors in the hypothalamus and pituitary gland, increasing GnRH, LH, and FSH secretion to stimulate natural testosterone production while preserving fertility.
Who Should Consider Enclomiphene?
Enclomiphene is typically prescribed for men with confirmed testosterone deficiency (total testosterone below 300 ng/dL) who are experiencing symptoms like fatigue, low libido, muscle loss, or mood changes.
Clinics Offering Enclomiphene
Enclomiphene FAQ
How much does Enclomiphene cost?
Compounded Enclomiphene costs $40-90/mo through TRT clinics. Brand-name versions (Androxal (not yet FDA-approved)) cost N/A (not commercially available) without insurance.
What are Enclomiphene side effects?
Common side effects include headache, nausea, hot flashes, visual disturbances (rare), fatigue. Most are manageable with proper monitoring.
How is Enclomiphene administered?
Enclomiphene is administered as a daily oral pill.
What doses is Enclomiphene available in?
Enclomiphene is available in 12.5mg/day, 25mg/day, 50mg/day doses.