Anastrozole Side Effects (2026)
Blocks the enzyme aromatase which converts testosterone to estradiol, used in TRT to manage elevated estrogen levels and prevent estrogen-related side effects like gynecomastia and water retention.
$10-30/mo
Compounded Price
Oral
Frequency
3
Dose Options
1995 (for breast cancer; off-label for TRT)
FDA Approved
Anastrozole Side Effects
Anastrozole can cause side effects, most of which are manageable with proper monitoring and protocol adjustments.
Common Side Effects
- Joint pain
- Fatigue
- Headache
- Hot flashes
- Bone density concerns with long-term use
Managing Side Effects
Regular bloodwork monitoring is the key to managing side effects. Your provider will track hematocrit, estradiol, PSA, and liver function to catch any issues early.
Clinics Offering Anastrozole
Anastrozole FAQ
How much does Anastrozole cost?
Compounded Anastrozole costs $10-30/mo through TRT clinics. Brand-name versions (Arimidex) cost $20-60/mo without insurance.
What are Anastrozole side effects?
Common side effects include joint pain, fatigue, headache, hot flashes, bone density concerns with long-term use. Most are manageable with proper monitoring.
How is Anastrozole administered?
Anastrozole is administered as a oral pill taken 1-3 times per week.
What doses is Anastrozole available in?
Anastrozole is available in 0.25mg 2x/week, 0.5mg 2x/week, 1mg 2x/week doses.