Anastrozole Guide (2026)
Blocks the enzyme aromatase which converts testosterone to estradiol, used in TRT to manage elevated estrogen levels and prevent estrogen-related side effects like gynecomastia and water retention.
$10-30/mo
Compounded Price
Oral
Frequency
3
Dose Options
1995 (for breast cancer; off-label for TRT)
FDA Approved
What Is Anastrozole?
Anastrozole is a Aromatase inhibitor (AI) that works by blocks the enzyme aromatase which converts testosterone to estradiol, used in trt to manage elevated estrogen levels and prevent estrogen-related side effects like gynecomastia and water retention. It was approved by the FDA in 1995 (for breast cancer; off-label for TRT) and is manufactured by AstraZeneca / Various generics.
Brand names include Arimidex. Anastrozole is administered as a oral pill taken 1-3 times per week.
How Anastrozole Works
Blocks the enzyme aromatase which converts testosterone to estradiol, used in TRT to manage elevated estrogen levels and prevent estrogen-related side effects like gynecomastia and water retention.
Who Should Consider Anastrozole?
Anastrozole is typically prescribed for men with confirmed testosterone deficiency (total testosterone below 300 ng/dL) who are experiencing symptoms like fatigue, low libido, muscle loss, or mood changes.
Clinics Offering Anastrozole
Anastrozole FAQ
How much does Anastrozole cost?
Compounded Anastrozole costs $10-30/mo through TRT clinics. Brand-name versions (Arimidex) cost $20-60/mo without insurance.
What are Anastrozole side effects?
Common side effects include joint pain, fatigue, headache, hot flashes, bone density concerns with long-term use. Most are manageable with proper monitoring.
How is Anastrozole administered?
Anastrozole is administered as a oral pill taken 1-3 times per week.
What doses is Anastrozole available in?
Anastrozole is available in 0.25mg 2x/week, 0.5mg 2x/week, 1mg 2x/week doses.