How to Read Your TRT Bloodwork
A clear, step-by-step guide to help you read your trt bloodwork. This guide applies to all TRT protocols.
Step-by-Step Guide
Check total testosterone: optimal range on TRT is typically 600-1000 ng/dL at trough (day of injection before next dose)
Check free testosterone: should be in the upper quartile of the reference range for your age
Review SHBG: high SHBG binds testosterone and reduces free T; low SHBG may indicate metabolic issues
Monitor estradiol (E2): optimal range on TRT is typically 20-50 pg/mL; too high causes water retention and gynecomastia
Check hematocrit and hemoglobin: hematocrit above 52-54% may require blood donation or dose reduction
Review PSA: establish a baseline before TRT and monitor for significant increases (>1.4 ng/mL rise in 12 months)
Check liver enzymes (AST, ALT) and lipid panel to monitor overall metabolic health
Review CBC for red blood cell count, white blood cell count, and platelet levels
Important Reminders
- Always follow your healthcare provider's specific instructions
- Testosterone is a controlled substance requiring a prescription and medical oversight
- Get regular bloodwork every 3-6 months to monitor your levels
- Report any unexpected symptoms to your provider promptly