How to Preserve Fertility on TRT
A clear, step-by-step guide to help you preserve fertility on trt. This guide is specific to HCG (Pregnyl/Novarel).
Step-by-Step Guide
Discuss fertility goals with your provider BEFORE starting TRT
Consider freezing sperm before starting testosterone if children are planned in the near future
Add HCG (250-500 IU 2-3 times per week) to your TRT protocol to maintain testicular function and sperm production
Consider enclomiphene as an alternative or adjunct to maintain LH and FSH stimulation
Get a semen analysis at baseline and periodically to monitor sperm count
If fertility is the primary concern, consider enclomiphene monotherapy as an alternative to testosterone injections
Be aware that fertility recovery after stopping TRT can take 6-12+ months and is not guaranteed
About HCG
HCG (Pregnyl / Novarel) is a Human chorionic gonadotropin administered as a Subcutaneous injection 2-3 times per week. The standard dosage options are 250 IU 3x/week, 500 IU 2x/week, 500 IU 3x/week, 1000 IU 2x/week.
Compounded hcg is available through TRT clinics at $30-80/mo, compared to the brand-name price of $100-300/mo.
Important Reminders
- Always follow your healthcare provider's specific instructions
- Testosterone is a controlled substance requiring a prescription and medical oversight
- Get regular bloodwork every 3-6 months to monitor your levels
- Report any unexpected symptoms to your provider promptly