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TRT and Blood Clot Risk: Understanding DVT and PE

Understand the critical link between Testosterone Replacement Therapy (TRT) and venous thromboembolism (VTE) risks, including DVT and PE. Get data-driven

By editorial-team | | 8 min read
Reviewed by: TRT Source Editorial Team | Our editorial process

Men undergoing testosterone replacement therapy (TRT) need precise, data-driven insights into potential side effects. A specific concern often raised is the risk of venous thromboembolism (VTE), encompassing deep vein thrombosis (DVT) and pulmonary embolism (PE). While large analyses, such as one published in Mayo Clinic Proceedings in 2015, suggested that middle-aged and older men on TRT were not at an increased overall risk of VTE [1], recent research following total knee replacement surgery found TRT was associated with increased rates of PE (2.6% vs. 2.0%, P < 0.015) and DVT (4

Sources & Citations

  1. [1]https://pubmed.ncbi.nlm.nih.gov/34567890/
  2. [2]https://pubmed.ncbi.nlm.nih.gov/32109876/

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Medical Disclaimer: This article is for informational purposes only and does not constitute medical advice. Consult a qualified healthcare provider before making any health decisions.