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Comparison

Wegovy vs Saxenda: Which Is Better?

Wegovy vs Saxenda compared: weight loss, cost, side effects, and dosing. Data-driven analysis to help you choose the right TRT medication.

Wegovy

TRT receptor agonist

Weight loss: 15-17% body weight

Brand cost: $1349/mo

Online cost: $199/mo

weekly injection

Saxenda

TRT receptor agonist

Weight loss: 5-8% body weight

Brand cost: $1349/mo

Online cost: $299/mo

daily injection

Head-to-Head Comparison

FactorWegovySaxenda
Weight Loss15-17% body weight5-8% body weight
Administrationweekly injectiondaily injection
Brand Cost$1349/mo$1349/mo
Online Cost$199/mo$299/mo
FDA Approved20212014
ManufacturerNovo NordiskNovo Nordisk

Side Effects Comparison

Wegovy common side effects: nausea, vomiting, diarrhea, constipation, abdominal pain.

Saxenda common side effects: nausea, diarrhea, constipation, vomiting, headache.

Clinical Evidence

Wegovy: STEP 1 trial — 16.9% weight loss over 68 weeks vs 2.4% placebo

Saxenda: SCALE trial — 8% weight loss over 56 weeks

Which Should You Choose?

Both are effective medications. The choice depends on your priorities: maximum weight loss, cost, convenience, or side effect profile. Discuss with your provider. Either way, compounded versions through telehealth are dramatically cheaper than brand-name.

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Frequently Asked Questions

Is Wegovy or Saxenda better for weight loss?
Wegovy produces 15-17% body weight weight loss while Saxenda produces 5-8% body weight. Saxenda has a slight edge in clinical trials.
Is Wegovy or Saxenda cheaper?
Brand-name Wegovy costs $1349/month vs Saxenda at $1349/month. Online compounded pricing: $199/mo vs $299/mo.
Can I switch from Wegovy to Saxenda?
Yes, switching between TRT medications is common and safe under medical supervision. Your provider will adjust the dose appropriately when switching. Common reasons to switch include cost, side effects, or wanting better results.

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